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BlueYard Capital
BlueYard Capital

Research Associate II, Phenotypic Screening



Palo Alto, CA, USA
Posted on Saturday, August 19, 2023


Rarebase is an early-stage, public benefit precision medicine company based in Palo Alto, California, working to deliver therapies for the millions of people living with rare genetic diseases that have no effective treatments. Utilizing our proprietary Function™ platform, we collaborate with families and patient communities personally affected by rare disease to identify therapies that can potentially target the underlying biology of a disease with the goal of effectively treating each individual patient within a year.

Function is focused on identifying FDA approved drugs that can be rapidly repurposed and prescribed off-label by physicians to rare disease patients. The cutting edge platform integrates cellular models of disease with functional genomics, high throughput screening, high content imaging and computational biology to recommend potential treatments that physicians can prescribe to rare disease patients. We are building a next-generation automated lab in Palo Alto and building a team to bring this transformational approach to rare disease patients worldwide.

Rarebase is backed by top-tier institutional investors, pharma and biotech angel investors, families personally affected by rare disease, and others that truly care about our mission to re-invent therapeutic development for genetic diseases. Our advisors are leaders in the biotech and genetic disease community.

What you’ll do

  • Cell line maintenance, expansion, and development, including stable transfections.
  • Cell line Quality Control including Immunocytochemistry (ICC), imaging and qPCR.
  • Support imaging based analysis and characterization of cells.
  • High throughput imaging and Analysis (Perkin Elmer, Phenix)
  • Concise and effective documentation, reporting and presentation of data
  • Participating in lab duties, including maintaining common reagents and lab supplies.

What you’ll bring

  • A B.S. with 1-3 years of substantial experience with mammalian cell culture techniques under BSL2 conditions is required.
  • Proficiency with cell maintenance, expansion, banking, and quality control assays is necessary.
  • Knowledge of basic cell culture procedures is required.
  • Experience with immunocytochemistry is required.
  • Experience with image acquisition and analysis is preferred.
  • Knowledge of molecular biological techniques, including nucleic acid extraction RT-PCR, and WB is a plus.
  • Excellent recording, organizational, and planning skills
  • Strong communication and interpersonal skills.
  • Team player with the ability to work independently.

Compensation Range

$80,000 - $110,000

What we offer

  • An opportunity to work closely with patient organizations on translational research.
  • Premium health, vision, and dental insurance
  • 401k
  • Competitive salary and equity in a growing, well-funded startup
  • Generous vacation policy

We are committed to developing an inclusive work environment for all employees, where diversity of thought, style, culture, and skill is valued in support of individual performance and potential, as well as our business goals and mission. We prohibit discrimination on the basis of race, color, religion, age, sex, national origin, disability status, genetics, protected veteran status, sexual orientation, gender identity or expression, or and other characteristic protected by federal, state or local laws.