Senior Scientist, Molecular Biology (Technology Development)
Biofidelity
IT
Cambridge, UK
Posted on Tuesday, December 13, 2022
Biofidelity is a revolutionary genomic technology company dedicated to unleashing the potential of genomics to transform human health and the world we live in. Our adaptive platform technology removes the noise from genomic data, providing only the information needed to make decision making less complex, faster, and more accurate.
At Biofidelity we are proud to have built a culture of humanity, openness and high expectations. We work towards well-defined goals, with a strong belief that we can make genomics globally accessible. Our people are keen to take responsibility for their work and share both their successes and challenges.
Alongside a competitive salary and opportunities for career development, we offer a comprehensive benefits package including private medical & dental care, bonus, share option scheme, pension, income protection and life insurance, cycle to work scheme, season ticket loan, 26 days per year holiday allowance and free physical training sessions.
The role
Biofidelity is expanding its Technology Development team responsible for the development of molecular diagnostic assays based on its core technology. We are seeking an experienced senior scientist to help us build and validate our product. This role will be primarily laboratory-based with a strong emphasis on IVD product development. This role reports to the Director of Technology Development.
Key responsibilities:
● Independent development and iterative experimentation to drive improvement of assays for clinical diagnostic testing
● Recommends innovative approaches, and/or expansion or curtailment of investigations based on experimental data or new scientific information arising from area of responsibility
● Design a complex multistep assay
● Independent analysis and interpretation of data and results, drawing out of conclusions and strategic recommendations
● Interaction with team members in a multidisciplinary environment to ensure communication of project-relevant progress
● Writing SOPs, reports and safety documentation
● Giving advice and training others to perform validated assays
● Presenting results to the team
● Leading projects involving additional team members
● Supervising and training responsibility for more junior members of the team
● Potential line management responsibility
Knowledge, Skills and Abilities:
● Strong background in molecular biology (essential)
● Strong background in NGS library preparation methodologies (essential)
● Strong experience with single molecule detection assays (essential)
● Broad understanding of assay development methodology including testing of sensitivity and specificity (NGS and others) (essential)
● Experience in hybridisation and capture methodologies (preferred)
● Highly motivated, team-oriented individual with strong attention to detail
● Demonstrate strong relationship building with colleagues across the organisation
● Ability to multi-task and problem-solve using novel approaches with a positive approach
● Possesses a flexible mindset and ability to successfully navigate in a small, fast-growing company
● Experience in biotechnology method development (preferred)
● Experience in the following areas:
o High-sensitivity molecular assay development
o Multiplexed PCR/qPCR/dPCR
o Development of assays detecting DNA/RNA target of interest
o Cancer diagnostics
Requisite Education and Experience / Minimum Qualifications:
● Proven experience in the development, optimisation and validation of clinical diagnostic assays
● PhD in a relevant subject with preference for molecular biology and oncology plus more than 5 years of relevant academic or industrial experience